After realizing that Sophia is growing up faster than he'd like, John buys himself a pet, but it doesn't get along well with Joan. Also, Heather accidentally sends Tyler a sexy text message, Jen and Greg try to help Samantha win her boyfriend back and Heather and Jen console Colleen and Matt over their break-up.
- Colin Hanks as Greg Short
- Betsy Brandt as Heather (Short) Hughes
- Thomas Sadoski as Matthew "Matt" Short
- Zoe Lister-Jones as Jennifer "Jen" Collins-Short
- Dan Bakkeddahl as Dr. Timothy "Tim" Hughes, M.D.
- Angelique Cabral as Colleen Brandon Ortega
- Niall Cunningham as Tyler Hughes
- Holly Barrett as Samantha "Sam" Hughes
- Giselle Eisenberg as Sophia Hughes
- James Brolin as John Bertram Short
- Dianne Wiest as Dr. Joan (Pirkle) Short
- Hunter King as Clementine
- Kelly Albanese as Kelly
- Alek Cole as Irving Rosenblatt (as Alek Brett Cole)
- Mimi Karsh as Dance