Season 2

The second season of the family sitcom as Life in Pieces which was premiered on October 27, 2016 and concluded on May 11, 2017 with the consists of 22 episodes.

Cast

 * Colin Hanks as Greg Short
 * Betsy Brandt as Heather (Short) Hughes
 * Thomas Sadoski as Matthew "Matt" Short
 * Zoe Lister-Jones as Jennifer "Jen" Collins-Short
 * Dan Bakkeddahl as Dr. Timothy "Tim" Hughes, M.D.
 * Angelique Cabral as Colleen Brandon Ortega
 * Niall Cunningham as Tyler Hughes
 * Holly Barrett as Samantha "Sam" Hughes
 * Giselle Eisenberg as Sophia Hughes
 * James Brolin as John Bertram Short
 * Dianne Wiest as Dr. Joan (Pirkle) Short
 * Hunter King as Clementine Hughes